Anti-Denosumab Polyclonal Antibody (PAA30301)

Rabbit

IgG

Polyclonal

Denosumab

ELISA: 1:4000-1:8000

Rabbit polyclonal to Prolia.

The product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays.

0.6 mg/ml

Purified by antigen affinity column.

CAS: 615258-40-7

ELISA

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface.