Anti-Ipilimumab Polyclonal Antibody (PAD17201)

Rabbit

IgG

Polyclonal

Ipilimumab

ELISA: 1:4000-1:8000

Rabbit polyclonal to Yervoy.

The product is specific for Ipilimumab. This antibody serves as an excellent positive control for Ipilimumab immunogenicity (ADA) assays.

0.27 mg/ml

Purified by antigen affinity column.

CAS: 477202-00-9

ELISA

Liquid

0.01M PBS, pH 7.4.

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells.