Anti-Ustekinumab Polyclonal Antibody (PAD84001)

Rabbit

IgG

Polyclonal

Ustekinumab

ELISA: 1:4000-1:8000

Rabbit polyclonal to Stelara.

The product is specific for Ustekinumab. This antibody serves as an excellent positive control for Ustekinumab immunogenicity (ADA) assays.

0.5 mg/ml

Purified by antigen affinity column.

CAS: 815610-63-0

ELISA

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Antibodysystem Anti-Ustekinumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Ustekinumab.