概述
-
货号
PAH02201
-
宿主
Rabbit -
同种型
IgG -
克隆类型
Polyclonal -
免疫原
Pembrolizumab -
经测试应用
ELISA: 1:4000-1:8000 -
靶标
Rabbit polyclonal to Keytruda. -
特异性
The product is specific for Pembrolizumab. This antibody serves as an excellent positive control for Pembrolizumab immunogenicity (ADA) assays. -
浓度
0.5 mg/ml -
纯化方式
Purified by antigen affinity column. -
Accession号
CAS: 1374853-91-4 -
应用
ELISA -
状态
Liquid -
保存溶液
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. -
稳定性和存储
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. -
背景
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Antibodysystem Anti-Pembrolizumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Pembrolizumab.
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