概述
-
货号
FHC13010
-
种属反应性
Human -
宿主
Mouse -
同种型
IgG1, kappa -
克隆类型
Monoclonal -
偶联物
Unconjugated -
靶标
GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A -
浓度
1 mg/ml -
内毒素水平
Please contact with the lab for this information. -
纯度
>95% as determined by SDS-PAGE. -
纯化方式
Protein A/G purified from cell culture supernatant. -
Accession号
P05106 -
克隆号
LM609
-
应用
FCM -
状态
Liquid -
保存溶液
0.01M PBS, pH 7.4. -
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
图片
参考文献
- The therapeutic antibody LM609 selectively inhibits ligand binding to human αvβ3 integrin via steric hindrance
- Monoclonal antibodies to αVβ3 (7E3 and LM609) inhibit sickle red blood cell–endothelium interactions induced by platelet-activating factor: Presented in part at the …
- Arming tumor-associated macrophages to reverse epithelial cancer progression
- Stromal cell-derived factor-1 inducing metastasis squamous cell carcinoma of head and neck induced via integrin ανβ3-CXC chemokine receptor 4/7 biological axis
- An antagonist of integrin αvβ3 prevents maturation of blood vessels during embryonic neovascularization
- Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via α3β1 integrin
- Palmitate up-regulates laminin expression via ROS/integrin αvβ3 pathway in HLSECs
- Reduced Intimal Thickening Following αvβ 3 Blockade is Associated with Smooth Muscle Cell Apoptosis
- Inhibition of corneal neovascularization by αv-integrin antagonists in the rat
- Integrin αvβ3‐targeted therapy for Kaposi's sarcoma with an in vitro‐evolved antibody
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