概述
-
货号
PAD62601
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宿主
Rabbit -
同种型
IgG -
克隆类型
Polyclonal -
免疫原
Dupilumab -
经测试应用
ELISA: 1:4000-1:8000 -
靶标
Rabbit polyclonal to Dupixent. -
特异性
The product is specific for Dupilumab. This antibody serves as an excellent positive control for Dupilumab immunogenicity (ADA) assays. -
浓度
0.5 mg/ml -
纯化方式
Purified by antigen affinity column. -
Accession号
CAS: 1190264-60-8 -
应用
ELISA -
状态
Liquid -
保存溶液
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. -
稳定性和存储
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. -
背景
Dupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4Rα) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling. Anti-Dupilumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Dupilumab.
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